The Fractured but Whole offers players the opportunity to play as a woman by 'retconning' gender in the game: the player has a conversation with the school counsellor, Mr Mackay, where the player-character is able to declare that they are, in fact, a girl. South Park: The Fractured But Whole builds on The Stick of Truth, where the players had to play as a male character.
He also has a minor appearance in South Park: The Stick of Truth. South Park Rally features a character named 'Big Gay Al', who is a stereotypically flamboyant gay man.